Comparison of Cytokine Responses with Anti-D and Intravenous Immunoglobulin in Idiopathic Thrombocytopenia
نویسندگان
چکیده
منابع مشابه
Comparison of cytokine responses with anti-d and intravenous immunoglobulin in idiopathic thrombocytopenia.
within 1–20 h after anti-D infusion [3], supporting the concept of cytokine immunomodulation with anti-D therapy. A recent paper by Del Vecchio et al. [4] showed that IL-10 levels at the onset may predict the course of patients with ITP, and higher levels have a positive outcome on disease remission within 1 year, while high thrombopoietin levels were not helpful in predicting the course of dis...
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introduction: acute idiopathic thrombocytopenic purpura (itp) is an autoimmune bleeding disorder of childhood caused by production of auto antibodies against platelets. the aim of the present study was to compare the efficacy of intravenous immunoglobulin (ivig) and intravenous anti-d(iv anti-d) in itp treatment. methods and materials: in a clinical trial, 43 children with acute itp referred to...
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SIR-The recent paper by Glatt and Anand [1] provides an excellent, comprehensive review of the natural history and treatment options with regard to HIV-related thrombocytopenia. We wish to discuss the efficacy of therapy with intravenous anti-rhesus D (Rho[D]) immunoglobulin in this setting. Glatt and Anand state that the drawbacks to intravenous anti-RHo(D) include lack of experience with its ...
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Twenty five children with chronic idiopathic thrombocytopenic purpura followed from 6-96 months in 7 Italian paediatric departments were treated with high dose immunoglobulin according to a multicentre protocol. Positive responses were observed in 20 of 25 patients (80%) and negative responses in 5 of 25 (20%). On previous steroid treatment 7 of 10 positive responders were steroid resistant and...
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Background: Children with idiopathic thrombocytopenic purpura who are treated with intravenous immunoglobulin therapy might experience a decline in their absolute neutrophil count. The aim of this study was to investigate the incidence of neutropenia following intravenous immunoglobulin therapy in children with idiopathic thrombocytopenic purpura undergoing intravenous immunoglobulin therapy. ...
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ژورنال
عنوان ژورنال: Transfusion Medicine and Hemotherapy
سال: 2013
ISSN: 1660-3818,1660-3796
DOI: 10.1159/000345740